GLP-1 Receptor Agonists: The Most Important Drug Class of Our Lifetime?

If you have been paying attention to cardiovascular medicine over the past decade, you have watched GLP-1 receptor agonists transform from diabetes drugs into one of the most powerful multi-system therapies in modern medicine. ...

The VO2 Max Trap: Why Chasing Cardio Fitness Alone Could Be Slowly Killing Your Heart

Let me start with a picture most people in the fitness world have never questioned.

You've seen them. The elite marathon runner crossing the finish line, lean to the bone, veins threading across arms that look li...

The Father of Modern Cardiology: A Tribute to Dr. Eugene Braunwald

August 15, 1929 – April 22, 2026

His Life, His Textbook, and the Legacy That Will Define Cardiology for Generations

"All cardiologists today have been touched by Dr. Braunwald through the training they received and the classical t...

Are GLP-1 Medications Destroying Your Muscle? Here Is What the Research Actually Shows.

The muscle wasting narrative around Ozempic and Wegovy has been everywhere. A 2026 study in Cell Reports Medicine just put it to the test with four preclinical studies and a human clinical trial.

If you or some...

Is Alcohol Safe for Your Heart? Here Is What the Science Actually Shows.

Decades of reassuring headlines about red wine and heart health have not aged well. Let's go through the real data, study by study.

Is alcohol safe for your heart? We have been told since the 1990s that red wine may offer som...

The Largest Meta Analysis Of Randomized Controlled Trials On Exercise And Heart Disease Outcomes Was Just Published

The largest study o exercise dropped. It's a meta analysis of only randomized control trials. Randomized control trials are the highest level of evidence. A meta analysis is an overvi...

New Non Steroidal Mineralocorticoid Receptor Antagonists In Heart Failure

There is a class of medications with decades of evidence behind them, a Class I guideline recommendation for heart failure, and mortality data that most drugs would envy. And yet they are prescribed to fewer than one in three...

Treating Two Types of Heart Failure: HFpEF and HFrEF

What Is Heart Failure? I get asked this every day.

Heart failure doesn't mean the heart has stopped working. Instead, it means the heart isn't pumping blood as well as it should. This causes fluid to build up in the body, leading to symptoms lik...

Comparing the ACC/AHA Guidelines To The European EAS Guidelines: Cholesterol Treatment

Just a few months apart, the Europeans and Americans have released Dyslipidemia Treatment Guidelines. They are getting closer to matching what myself and Dr. Thomas Dayspring published in 2023 in the Cholesterol ...

The Cholesterol Time Bomb: Why Young, Healthy People Still Get Heart Disease

Can young, healthy, metabolically pristine individuals get heart disease if all they have is high LDL? I get asked this question a lot and it has been tested and studied extensively.

What if you have no insulin resistance...